This news was extremely unsettling. Inshallah, Pakistan & India will be able to recover from the horrific damages that were the result of the 7.6 earthquake. However, we all know that much of the good works and help will bypass those who are in need of it the most.
Give generously to your friends and family, and don't forget the noble organizations that provide much needed services as well - food, medicine, clothing, education, and temporary shelter.

Below are some links. If you know of any other reputable organiztions, please let me know and I will add them to the list.
My prayers are with those during these trying times.

Citizens' Foundation www.thecitizensfoundation.org query_dir=how_you_can_help& query_focus=donation_methods

Edhi Foundation - Contact the office that is most convinient for you to give a donation. www.paks.net